Built-in versatility for the pharmaceutical industry
The MULTI-PROCESSOR™ sets the versatility standard. Available
in a range of sizes to meet customer requirements - from the MP-MICRO™
development unit to full-scale production equipment - it maximises flexibility
by enabling users to attach modules to the central fluid bed for specific
functions: blending, granulating, drying, pelletizing, and coating. The
MULTI-PROCESSOR™ is the ideal instrument for formulation, process development,
production of clinical material, through to full-scale production.
Process Modules
Blending & Granulating, Drying, Pelletizing and
Coating
The MULTI-PROCESSOR™ offers both a spray
dryer granulator and a top spray granulator. A pelletizing module and
PRECISION COATER™, are the solution to forming, pelletizing
and coating particles of varying sizes.
Precision-Coater™
The Precision-Coater™i s used for
smaller particles, such as powders, granules, seeds, crystals, pellets, and
small tablets.The product is coated and partially dried by being blown upward
through a central column with atomized liquid and drying air. The material
falls into the outer part of the container where heated air completes the
drying process. On reaching the air distributor at the base of the module, the
product flows again into the central column for further coating.This process
continues until the specified degree of coating is obtained.
Special features
- High spray rates for short processes
-
Highly controlled product movement
- Minimal agglomeration or granulation
Drying
Warm air is blown through a perforated
distributor to rapidly and gently dry materials until the required residual
moisture content is reached. Moisture evaporated from the product is exhausted
with the drying air.
Special features
- Selection of air distributors
- Short
process time
Top Spray Granulator
The top spray granulator
agglomerates finer particles into larger, free flowing granulates in a one-pot
process. Ingredients are mixed and pre-heated by an upward flow of heated air.
Granulation occurs by spraying liquid into the fluidized powder. The granules
are subsequently dried with heated air. The top spray granulator can also be
used for top spray coating, layering from liquids, and instantizing.
Special features
- One pot process
- Selection of air
distributors
Spray Dryer Granulator
The spray dryer granulator
transforms suspensions or solutions into dry, free-flowing, dustless granules.
A suspension or solution of the substance to be dried is sprayed onto warm air,
simultaneously drying and agglomerating the product. Batch or continuous
discharge is available - in the continuous mode, the product is discharged at a
controlled rate to maintain an optimum bed height.
Special features
- Compact unit
- Easy scale-up
- Batch or
continuous discharge
Precision-Granulator™
A rotating high velocity air
stream is established in the central agglomeration tube. Particles are picked
up at the base of the tube and accelerated by the air stream. The particles
come into contact with liquid droplets produced from the spray nozzle at the
base of the tube \ the relative velocity of air, liquid droplets and particles
are high so wetting is efficient and drying begins almost immediately. Most of
the feed material is in the outer “holding area”, where the gas velocity is
very low. Attrition is greatly reduced. The gas humidity is also low in the
holding area so the material is dry not sticky. Individual particles may make
repeated cycles (typically from 10 to 1,000) through the tube, allowing very
large agglomerates to be built up.