Current Good Manufacturing Practices increasingly require that product is fully contained during processing to protect operators and environment. Integrated process systems not only offer containment but improved productivity through automation, increased yield and efficient cleaning procedures.
GEA Pharma Systems is uniquely qualified to provide state-of-the-art integrated High Shear Mixer Granulator and Fluid Bed technology. Drawing on the world class expertise of GEA Pharma Systems companies, we offer fully integrated turnkey installations including fluid bed process equipment combined with Top- and Bottom-drive High Shear Mixer-Granulators from Aeromatic-Fielder and Collette. Our service includes design, installation assistance, commissioning, process validation, as well as training, and technical support. Installation, operation qualification and documentation are carried out according to FDA/GAMP guidelines.
Using proven standard components, GPS can supply both simplicity and flexibility in plant design. User-selected process options, cleaning equipment, control systems and PAT technologies combine in a system to meet process requirements exactly. This approach ensures that qualification and validation procedures are kept to a minimum.
Through-the-wall configuration
Through-the-wall offers the best option in terms of cleanliness, maintenance and ATEX. By keeping the motors out of the process room, you are preventing risk of contamination coming from these difficult to clean items. Maintenance is carried out from the technical area, minimising the need for the maintenance engineer to work in a GMP area. This makes the job easier and
again reduces the risk of contamination. For ATEX, the design allows us to classify the technical area as safe. This avoids the need for costly flameproof motors, making the upgrade for working with solvents much easier.