Process Engineering + Online Analysis + Process Modelling = Process
understanding
Aeromatic-Fielder (part of GEA Pharma Systems group) has
integrated its knowledge and experience in pharmaceutical granulation and
drying processes to help operators monitor and control the process in an easy
and self explanatory way. Depending on the automation and reporting
requirements, Aeromatic-Fielder can offer a control system which
provides the operator with all necessary process information in a clear and
easy to understand way.
Controls
The PLC front panel key-pad and builtin monitor are used for recipe
programming and real-time process MIMIC display. For optimum compatibility with
existing plant control strategies, fluid bed systems are available with a
choice of manual or FDA compliant automated controls. Programmable logic
controller (PLC) and PC-based options offer a wide range of recipe handling,
data acquisition and network communication functions.
GEA Pharma Systems integrate process engineering and PAT to provide
Process Intelligence
The FDA’s PAT (process analytical
technology) initiative has enabled GEA Pharma Systems to combine its equipment
design skills and process engineering know-how in order to integrate online
(PAT) analysers into its process systems in a way which can provide real
insight into the operation of the process and help customers achieve key
product quality target .
The goal of the PAT initiative is to ensure that pharmaceutical products are
manufactured using processes which are understood and monitored so that the key
quality characteristics of the
products can be actively controlled.
Combining process monitoring using online analysers, together with
solid process engineering principles and advanced process modelling techniques
will enable processes to be actively
controlled in order to compensate for
minor input variations (eg. raw materials) so that the specifications for the
final product will be closer to the ideal target.
Using process models
to identify the process conditions that highlite products which perform best in
subsequent processes will enable the whole production process to be targeted
towards the performance of the final dose rather than just optimising each unit
operation individually. GEA Pharma Systems wide scope gives it a unique
perspective on the complete process.