Here you will find all Technical Articles that cover the technology: Spray Drying
Pharmaceutical actives are mainly produced by biotechnology or chemical methods, normally involving a drying step as one of the very last unit operations. Here the focus of interest is mainly on the residual moisture or solvent content and also in the prevention of thermal degradation. The physical appearance of the material is not of great interest at that time because this is mostly modified during secondary production.
In secondary production, the solid dosage form is manufactured by blending the active with the necessary excipients. The next step is typically to form granules from this mixture by the means of wet granulation. After this a drying step is required. The reason for this granulation/drying operation is that modern high-speed tablet presses require materials with excellent flow properties in order to produce tablets with the required homogeneity and weight consistency.