Spray Dryers for the Pharmaceutical Industry
Niro has developed a completely new series of spray dryers dedicated to the pharmaceutical industry manufacturing. The new dryers, named PHARMASD™ (PSD) have been designed using standard modules that incorporate all the required features necessary for cGMP production in the environment of a pharmaceutical plant.
The philosophy behind the design is that a combination of standardised modules is built together to meet the requirement for a specific duty. Therefore, dryers of equal capacity may be completely different with respect to design, configuration and physical size. This allows Niro to focus specifically on the needs of the customer and the demands of the process without physical limitations to the design of the equipment.
The PSD dryers either use hot air or nitrogen as drying gas. Nitrogen is used when drying non-aqueous compounds. The dryers can be designed for drying of a wide range of compounds that are based on acetone, methylene chloride, ethanol, and other organic solvents. The drying process and product characteristics vary greatly, depending on the solvent used.
PHARMASD™ design options:
- Equipment for closed cycle operation
- Facilities for hot gas sanitisation
- Specially designed pharmaceutical flanges for duct connections
- Construction materials meeting FDA requirements
- HEPA filters for gas streams
- Special air disperser design
- Swirl cone for chamber access - no chamber door with risk for contamination
- CIP equipment
- As with all Niro plant equipment, each system component meets the strictest requirements and regulatory standards.
The PSD range of pharmaceutical dryers extends from the PSD-1 with a nominal drying gas rate of 80kg/hr up to the PSD-7 with a nominal drying gas rate of 4,000 kg/hr.